@InProceedings{Machado:2006:InStPo,
               author = "Machado, Alexei Manso Correa",
          affiliation = "{PUC Minas}",
                title = "Increasing statistical power in medical image analysis",
            booktitle = "Proceedings...",
                 year = "2006",
               editor = "Oliveira Neto, Manuel Menezes de and Carceroni, Rodrigo Lima",
         organization = "Brazilian Symposium on Computer Graphics and Image Processing, 19. 
                         (SIBGRAPI)",
            publisher = "IEEE Computer Society",
              address = "Los Alamitos",
             keywords = "multiple comparison correction, image registration, Bonferroni 
                         correction.",
             abstract = "In this paper, we present a novel method for estimating the 
                         effective number of independent variables in imaging applications 
                         that require multiple hypothesis testing. The method increases the 
                         statistical power of the results by refuting the assumption of 
                         independence among variables, while keeping the probability of 
                         false positives low. It is based on the spectral graph theory, in 
                         which the variables are seen as the vertices of a complete 
                         undirected graph and the correlation matrix as the adjacency 
                         matrix that weights its edges. By computing the eigenvalues of the 
                         correlation matrix, it is possible to obtain valuable information 
                         about the dependence levels among the variables of the problem. 
                         The method is compared to other available models and its 
                         effectiveness illustrated in a case study on the morphology of the 
                         human corpus callosum. .",
  conference-location = "Manaus, AM, Brazil",
      conference-year = "8-11 Oct. 2006",
                  doi = "10.1109/SIBGRAPI.2006.27",
                  url = "http://dx.doi.org/10.1109/SIBGRAPI.2006.27",
             language = "en",
                  ibi = "6qtX3pFwXQZG2LgkFdY/LJyAe",
                  url = "http://urlib.net/ibi/6qtX3pFwXQZG2LgkFdY/LJyAe",
           targetfile = "machado-increasing.pdf",
        urlaccessdate = "2024, May 03"
}